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KMID : 0372919880090010011
Journal of Biomedical Engineering Research
1988 Volume.9 No. 1 p.11 ~ p.16
A Study of on the Optimal Vaccinaton using Pontryagin¡¯s Minimum Principle



Abstract
The optimum control theory has been applied to the problem of finding the most economic use of active and passive immunization controls. Application of Pontryagin¡¯¡¯¡¯¡¯s Minimum Principle to this case, involving functions of delayed control has been demonstrated and a procedure has been developed for the numerical solution of the resulting control problem. Using the numerical procedure, optimum control strategies have been obtained for different values of reported case cost.
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